Columbia University Medical Center

DEPARTMENT OF NEUROSCIENCE

Mark Churchland, PhD

Mark Churchland, PhD
  • Department of Neuroscience
  • Assistant Professor of Neuroscience

The brain is not only a remarkable computational organ – capable of feats that stymie the best computers and robots – it is the seat of who we are and all we think.  Yet despite such romantic notions, modern systems neuroscience has principally asked how the brain transforms inputs into outputs.  This approach has deep historical roots – Descartes, Sherrington – and fabulous modern successes – Mountcastle, Hubel and Wiesel.  Yet the brain is clearly more than a glorified input-output device.  The neural networks within it do not just respond to external stimuli, they also generate their own activity.  A principal goal of my laboratory is to study the neural dynamics responsible for this ability.  In particular, I study how primary motor cortex generates the rich temporal patterns of neural activity that are responsible for moving the body.  My laboratory also focuses on translating basic science knowledge regarding dynamics into better ‘neural prostheses’: brain-machine interfacesthat directly translate neural activity into movement, thus bypassing an injured limb or spinal cord.

Lab Locations

Jerome L. Greene Science Center

3227 Broadway
L6-004
New York, NY 10027

Phone:
(212) 853-1068
Email:
mc3502@columbia.edu

Committees/Societies/Memberships

Co-director, Grossman Center for the Statistics of Mind

Member, Kavli Institute for Brain Science

Member, Behavior Research

Honors & Awards

McKnight Scholar Award

Sloan Research Fellow

NIH Director's New Innovator Award Program

Searle Scholars Program

Burroughs Wellcome Fund Career Award in the Basic Biomedical Sciences

Lab Website

Research Interests

Theoretical neuroscience
Motor systems
Cognitive/Systems neuroscience
Systems and circuits

Lab Members

Publications

  • Churchland MM. (2015). Using the precision of the primate to study the origins of movement variability. Neuroscience 296, 92-100.
  • Kaufman MT, Churchland MM, Ryu SI, Shenoy KV. (2014). Cortical activity in the null space: permitting preparation without movement. Nat Neurosci 17, 440-448.
  • Shenoy KV, Sahani M, Churchland MM. (2013). Cortical control of arm movements: a dynamical systems perspective. Annu Rev Neurosci 36, 337-359.
  • Kaufman MT, Churchland MM, Shenoy KV. (2013). The roles of monkey M1 neuron classes in movement preparation and execution. J Neurophysiol 4, 817-825.
  • Gilja V, Nuyujukian P, Chestek CA, Cunningham JP, Yu BM, Fan JM, Churchland MM, Kaufman MT, Kao JC, Ryu SI, Shenoy KV. (2012). A high-performance neural prosthesis enabled by control algorithm design. Nat Neurosci 15, 1752-1757.
  • Churchland MM, Abbott LF. (2012). Two layers of neural variability. Nat Neurosci 15, 1472-1474.
  • Churchland MM, Cunningham JP, Kaufman MT, Foster JD, Nuyujukian P, Ryu SI, Shenoy KV. (2012). Neural population dynamics during reaching. Nature 487, 51-56.
  • Shenoy, K.V., Kaufman, M.T., Sahani, M., and Churchland, M.M. (2011). A dynamical systems view of motor preparation: Implications for neural prosthetic system design. In Progress in Brain Research: Enhancing Performance for Action and Perception, A. Green, E. Chapman, J.F. Kalaska, and F. Lepore, eds. (Elsevier).
  • Churchland, M.M., Cunningham, J.P., Kaufman, M.T., Ryu, S.I., and Shenoy, K.V. (2010a). Cortical Preparatory Activity: Representation of Movement or First Cog in a Dynamical Machine? Neuron 68, 387-400.
  • Churchland, M.M.**, Yu, B.M.**, Cunningham, J.P., Sugrue, L.P., Cohen, M.R., Corrado, G.S., Newsome, W.T., Clark, A.M., Hosseini, P., Scott, B.B., Bradley D.C., Smith M.A., Kohn A., Movshon J.A., Armstrong K.M., Moore T., Chang S.W., Snyder L.H., Lisberger S.G., Priebe N.J., Finn I.M., Ferster D., Ryu S.I., Santhanam G., Sahani M., and Shenoy K.V. (2010b). Stimulus onset quenches neural variability: a widespread cortical phenomenon. Nat Neurosci 13, 369-378.
  • Churchland, M.M., Yu, B.M., Sahani, M., and Shenoy, K.V. (2007). Techniques for extracting single-trial activity patterns from large-scale neural recordings. Curr Opin Neurobiol 17, 609-618.
  • Churchland, M.M., and Shenoy, K.V. (2007). Delay of movement caused by disruption of cortical preparatory activity. J Neurophysiol 97, 348-359.
  • Churchland, M.M., Afshar, A., and Shenoy, K.V. (2006). A central source of movement variability. Neuron 52, 1085-1096.