- Department of Neuroscience
- Assistant Professor of Neuroscience
We study how neurons in the brain motivate our thoughts and behavior: how we learn what things in the world are good and bad, and how we use this knowledge to gather the good things and banish the bad things! A great deal of work, including our own, has shown how neural systems motivate us to seek concrete, physical rewards that satisfy our basic needs (e.g. appetitive rewards like food and water). However, we are especially interested in more abstract forms of reward that satisfy higher-level goals, such as our desire to learn about the world around us.
As an example of our work in this vein, we have uncovered neural systems that motivate “information seeking”, a phenomenon in which animals choose to gather information that helps them predict future rewards. We found evidence that some of the same neural systems which promote actions to seek conventional appetitive rewards also promote actions to seek information about those rewards, effectively treating information as a reward in its own right.
These findings raise fundamental questions about how rewarding experiences are constructed by the brain. It may seem straightforward to imagine a ‘reward detecting neuron’ for physical substances like food and water, but how the brain generates more abstract rewarding experiences is largely unknown. In our lab we address this and other questions using a combination of methods, including experiments to record and manipulate neuronal activity, psychophysics experiments in humans and animals, and computational modeling to advance new theories of learning and motivation.
Education & Training
630 West 168th Street
New York, NY 10032
- (212) 342-3805
Member, The Kavli Institute for Brain Science
Member, The Society for Neuroscience
Bromberg-Martin E.S., Hikosaka O. (2011) Lateral habenula neurons signal errors in the prediction of reward information.
Nature Neuroscience 14: 1209-1216.
Bromberg-Martin E.S., Matsumoto M., Hikosaka O. (2010) Dopamine in motivational control: rewarding, aversive, and alerting.
Neuron 68: 815-834.
Bromberg-Martin E.S., Matsumoto M., Nakahara H., Hikosaka O. (2010) Multiple timescales of memory in lateral habenula and dopamine neurons.
Neuron 67: 499-510.
Bromberg-Martin E.S., Matsumoto M., Hikosaka O. (2010) Distinct tonic and phasic anticipatory activity in lateral habenula and dopamine neurons.
Neuron 67: 144-155.
Bromberg-Martin E.S., Hikosaka O., Nakamura K. (2010) Coding of task reward value in the dorsal raphe nucleus.
Journal of Neuroscience 30: 6262-6272.
Bromberg-Martin E.S., Hikosaka O. (2009) Midbrain dopamine neurons signal preference for advance information about future reward.
Neuron 63: 119-126.